Recent magnetic resonance imaging and pathological studies have indicated that axonal loss is a major contributor to disease progression in multiple sclerosis. 1 H magnetic resonance spectroscopy, through measurement of N -acetyl aspartate, a neuronal marker, provides a unique tool to investigate this. Patients with primary progressive multiple sclerosis have few lesions on conventional MRI, suggesting that changes in normal appearing white matter, such as axonal loss, may be particularly relevant to disease progression in this group. To test this hypothesis (...) NAWM was studied with MRS, measuring the concentration of N -acetyl derived groups. Single-voxel MRS using a water-suppressed PRESS sequence was carried out in 24 patients with primary progressive multiple sclerosis and in 16 age-matched controls. Ratios of metabolite to creatine concentration were calculated in all subjects, and absolute concentrations were measured in 18 patients and all controls. NA/Cr was significantly lower in NAWM in patients than in controls, as was the absolute concentration of NA. There was no significant difference in the absolute concentration of creatine between the groups. This study supports the hypothesis that axonal loss occurs in NAWM in primary progressive multiple sclerosis and may well be a mechanism for disease progression in this group. (shrink)

While Nozick and his sympathizers assume there is a widespread anti-hedonist intuition to prefer reality to an experience machine, hedonists have marshalled empirical evidence that shows such an assumption to be unfounded. Results of several experience machine variants indicate there is no widespread anti-hedonist intuition. From these findings, hedonists claim Nozick's argument fails as an objection to hedonism. This article suggests the argument surrounding experience machines has been misconceived. Rather than eliciting intuitions about what is prudentially valuable, these intuitive judgements (...) are instead calculations about prudential pay-offs and trade-offs. This position can help explain the divergence of intuitions people have about experience machines. (shrink)

We examined here whether people believe consumers of natural foods are more virtuous than consumers of unnatural foods. In Study One we asked student participants (n = 84; 77 female, M age = 19.5) to form an impression of another person based solely upon whether they ate natural or unnatural foods, these being determined in a pilot survey. On an open response format, participants reported more positive moral and health traits in consumers of natural foods. These findings were further confirmed (...) using rating-based evaluations. In Study Two we determined if this belief in the virtuousness of natural food consumers translated into behaviour. Student participants (n = 40; 25 female, M age = 20.2) played a trust game, exchanging tokens with a fictitious player. Incidental diet information about the fictitious player was provided, with participants in one group playing against a natural food consumer and those in another against an unnatural food consumer. Participants who played against a natural food consumer behaved as if they trusted this person more, and their performance on the game was predicted by how moral they felt the fictitious player was, but not by other attributes such as health. These findings suggest that people believe consumers of natural food are more virtuous, and we suggest this is driven by the altruistic attitudes that people believe to be associated with natural food consumption. (shrink)

Professor Stevenson's valuable paper [5] calls attention to a number of discrepancies between ‘if’ in English and its usual translation into the horseshoe of material implication. “This is not a reason for distrusting the horseshoe,” he notes, “which is useful so long as it is taken to mean just what it is defined to mean; and it is not a reason for distrusting our English if's, which in spite of their ambiguities are indispensable to our daily discourse”. Accordingly, (...) class='Hi'>Stevenson proposes to develop a “richer logic” than the ordinary one, by adding as primitives certain sentential connectives. He speaks throughout in the old terminology of “propositions” rather than in that of the sentences or statements used to express them. Thus he speaks of atomic and molecular propositions, somehow no doubt as real entities in the world, where talk of atomic and molecular sentences would save him from implicit involvement in the notorious difficulties connected with atomic facts. Finally, the inner structure of atomic sentences, and therewith of molecular ones, is never considered. Many molecular sentences contain quantifiers in interesting ways, the clarification of which would seem essential in getting at their structure. Stevenson, however, has no concern with quantifiers, and does not exhibit the quantificational structure of the English sentences considered. (shrink)

A new characterization of tabularity in tense logic is established, namely, a tense logic L is tabular if and only if $\mathsf {tab}_n^T\in L$ for some $n\geq 1$. Two characterization theorems for the Post-completeness in tabular tense logics are given. Furthermore, a characterization of the Post-completeness in the lattice of all tense logics is established. Post numbers of some tense logics are shown.

Taylor, R. A tribute.--Epistemology: Cornman, J. W. Chisholm on sensing and perceiving. Ross, J. F. Testimonial evidence. Lehrer, K. Reason and consistency. Keim, R. Epistemic values and epistemic viewpoints. Hanen, M. Confirmation, explanation, and acceptance. Canfield, J. V. "I know that I am in pain" is senseless. Steel, T. J. Knowledge and the self-presenting.--Metaphysics: Cartwright, R. Scattered objects. Duggan, T. J. Hume on causation. Arnaud, R. B. Brentanist relations. Johnson, M. L., Jr. Events as recurrables.--Ethics: Stevenson, J. T. On (...) doxastic responsibility. Feldman, F. World utilitarianism. Lamb, J. W. Some definitions for the theory of rules. Donnelly, J. Suicide: some epistemological considerations. (shrink)

Weitz claims that humanistic philosophy requires open concepts. Concepts are said to be "neutral intermediaries between words and things". For Frege they must be sharply defined; for Weitz open concepts are sets of criteria that are either nonnecessary or nonsufficient or both in the definition of something, though they may be rejectable or undebatable. Thus he dismisses with Karl Popper "essentialism," and thus also Platonism and Aristotelianism. He finds early suggestions of open concepts in C. L. Stevenson’s "Persuasive Definitions," (...) Friedrich Waismann’s "Verifiability," H. L. A. Hart’s "defeasible contracts," Wittgenstein’s "family resemblances," and W. B. Gallie’s "Essentially Contested Concepts." He asserts "... the discovery of open concepts—not just ambiguous, vague or woolly words, which open concepts and their conveying words are not—throws new light on the whole problem of conceptualization". Real definitions then can be only of closed concepts, such as may prevail in science; while the fruits of open concepts are especially characteristic of the humanities, though certainly not limited to them. (shrink)

Federal law under the Individuals with Disabilities in Education Improvement Act stipulates that services provided to students with diagnosed disabilities must be individualised based on the as...

Olthuis makes a singular contribution in bringing the "Philosophy of the Law-Idea" to the attention of philosophers who lack other access to this development in contemporary Dutch thought. His presentation concentrates on applications to ethics. He begins with a thorough exposition of G. E. Moore's ethical theory, to which he applies "history's critique"--a resumé of Ayer and Stevenson, of Oxford meta-ethics, and of the "new wave" of naturalism set in motion by Anscombe and Foot in 1958. Olthuis finds that (...) neither Moore nor the subsequent philosophers could long stave off the irreconcilable extreme of absolute value or absolute relativism. "... the main source of difficulty in the constrictive nature of the... ontological schema," and, underlying that, in the claim that theoretical thought is neutral. In a valuable final chapter, he presents a "perspective for a way out" based on work by H. Dooyeweerd and D. H. Th. Vollenhoven. One key to their Philosophy of the Law-Idea lies in "norm-laws." Like "natural" laws, what is subject to them cannot withdraw. Unlike "natural" laws, they demand human acknowledgment to be fulfilled. He rejects both "ought" and "goodness" as adequate primitive concepts for ethics in favor of stress upon its irreducible "sphere-sovereignty." The cosmos stands under a structural law-order, made up of many modal laws determining the many modalities of reality. Within the normative, ethics is only one special modal science. Its job is to investigate the ethical norm-law, that which is subject to it, and the correlations between these two.--M. B. M. (shrink)

When people engage in conversation, they tailor their utterances to their conversational partners, whether these partners are other humans or computational systems. This tailoring, or adaptation to the partner takes place in all facets of human language use, and is based on a mental model or a user model of the conversational partner. Such adaptation has been shown to improve listeners' comprehension, their satisfaction with an interactive system, the efficiency with which they execute conversational tasks, and the likelihood of achieving (...) higher level goals such as changing the listener's beliefs and attitudes. We focus on one aspect of adaptation, namely the tailoring of the content of dialogue system utterances for the higher level processes of persuasion, argumentation and advice-giving. Our hypothesis is that algorithms that adapt content for these processes, according to a user model, will improve the usability, efficiency, and effectiveness of dialogue systems. We describe a multimodal dialogue system and algorithms for adaptive content selection based on multi-attribute decision theory. We demonstrate experimentally the improved efficacy of system responses through the use of user models to both tailor the content of system utterances and to manipulate their conciseness. (shrink)

Essays centred on the methods, pleasures, and pitfalls of architectural interpretation.

Subtitled "Studies in Ethical Analysis," this collection of eleven essays, most of which have previously appeared in journals, deals with a number of problems central to modern ethical theory: the emotive interpretation of ethical language, persuasive definitions and their role in ethical reasoning, the cognitive versus emotive conceptions of ethics: many of these problems were first raised and examined by Stevenson in his earlier book Ethics and Language. Other essays are of a less retrospective nature: studies on Moore and (...) Dewey, naturalism and relativism in ethics, and a general discussion of the relations of linguistic analysis to philosophy as a whole. Stevenson is mainly concerned with analytical, as opposed to descriptive, ethics; and he completely avoids the topics of normative ethics except for a brief survey. The approach to ethics is therefore restricted, but there is enough here to interest the philosopher whose main area lies outside of ethics; although it presupposes no acquaintance with the author's previous work, some of the questions on emotivism and persuasive language are more motivated when seen in the context of that work.—P. J. M. (shrink)

First published in 1995. Routledge is an imprint of Taylor & Francis, an informa company.

First published in 1995. Routledge is an imprint of Taylor & Francis, an informa company.

Two major functions of the visual system are discussed and contrasted. One function of vision is the creation of an internal model or percept of the external world. Most research in object perception has concentrated on this aspect of vision. Vision also guides the control of object-directed action. In the latter case, vision directs our actions with respect to the world by transforming visual inputs into appropriate motor outputs. We argue that separate, but interactive, visual systems have evolved for the (...) perception of objects on the one hand and the control of actions directed at those objects on the other. This 'duplex' approach to high-level vision suggests that Marrian or 'reconstructive' approaches and Gibsonian or 'purposive-animate-behaviorist' approaches need not be seen as mutually exclusive, but rather as complementary in their emphases on different aspects of visual function. (shrink)